For the first time the Ebola virus has been detected in 1976 when there was two outbreaks in the same time: in Nzara, Sudan plus in Yambuku, Democratic Republic of Congo

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Qualitative Management Tools

The qualitative mechanisms rely on information which cannot be easily measured. It heavily depends upon user judgment into the analysis and interpretation of results. As an element of quality control, BMW uses various qualitative tools of management to determine the level to which quality control is ensured into the company. Such tools include:

  1. Reputation

Present criterion cannot be expressed in numerical terms. The company gains reputation from its luxurious automobiles which are well-designed and have now a powerful level. It is gained for satisfaction by the customers who make the brand grow to a worldwide recognition (Daniel, 2014).

  1. Brand Strength

The company’s brand is just a strong feature in the success of its worldwide operations. However, this is a qualitative aspect which cannot be attached to any numeric values. Not surprisingly, it’s important in determining the level of this company services and products’ success in meeting and exceeding the requirements and expectations of this customers. The company’s quality products are in charge of the strong BMW brand.

How the Qualitative and Quantitative Tools Support Decision Making

When making decisions, the organization has to count on both qualitative and quantitative tools, since they supplement each other. As an example, customer comments may possibly not be easily expressed in numbers by way of a qualitative analysis, but will give a suitable interpretation as to the level to which customers are satisfied. The organization can use quantitative data on how many customers who buy its automobiles, the complaints received therefore the warranty claims from the company. It allows gauging the success of its services and products available in the market. Statistical methods in such situation provide efficient results on when to produce the number and where you should sell.

The qualitative analysis in some instances may give ambiguous results, though it could contain extra information. As an example, it could indicate the impression of this consumers regarding the BMW automobiles alongside the undeniable fact that customers would appreciate faster delivery of this automobiles. Such extra information is not available into the quantitative measures.restate thesis in different words The equipment permit the company to predict sales growth, schedule production operations and ability to create. Further, the consumer feedback into the qualitative measures provides company valuable information to redesign their automobiles to meet up with the customers’ expectations. The blend of both measures helps in the act of appropriate decision-making (Mencl, 2012).

BMW Workflow to Enhance Continuous Improvement

as an element of continuous improvement, BMW has generated checks into the course of manufacturing to cater for quality services and products. Into the manufacturing, processing and procurement functions, the organization has organized the operations in a fashion that improvement is ensured in every step of production. In the course of engineering, automobiles are tailored to meet up with consumer demands. The organization has embarked on establishing a wide coverage through its distributorships on earth to facilitate faster service delivery.

The workflow programs into the company provide BMW by having a competitive advantage through its growth prospects, profitability, shaping the future therefore the usage of the newest production and distribution technologies. Beginning the style of this automobiles, their quality is ensured till the automobile is brought to the consumer. The organization aims at constant developing the workflow to offer customers the ultimate experience with the BMW automobiles. The success factors into the workflow will be the employees, shareholders and corporate management mechanisms. As a result, they work together to supply the finest quality of products (Reeves, 1994). Within the continuous improvement, BMW is taking care of a formula to boost the external networks as well as communications aided by the relevant stakeholders groups. Through the production chain, the key challenge could be the increasing fuel expenses alongside the fuel consumption and emission requirements which vary into the countries of operation. It has placed a strong demand to have the engines modified to meet up with the regulatory policies of this countries when the automobiles is used.

Workflow Improvement Plan for BMW

The use of quality management tools presents critical methods to designing systems for production optimization. As an element of the continuous improvement, the organization has to make use of both qualitative and quantitative quality control mechanisms for exemplary decision-making strategies. Further, track of the equipment efficiency is important to determine the most readily useful tool to make use of when coming up with predictions. Having more tools into the quality control practice will result in improvement into the company’s ability to deliver the consumer expectations.

The flow of activities form one assembling section to the other has to be keenly checked to allow most of the inefficiencies to be detected and corrected in a timely manner. It could be authorized through locating most of the sections for the car assembling at one site. It will allow quality to be easily determined and corrections made. Into the improvement plan, each work group should pass quality to another location production team into the chain. It will also help in determining the inefficiencies into the workflow program and corrective measures will be used to boost the specific situation. So that you can fully monitor the workflow program, BMW could consider having a good management team, which can be dedicated to delivering quality towards the customers, and ensuring a cross-functional coordination of all of the the production sections. The key objective of this quality team is always to make sure process optimization and reduce consumer complaints by identifying mistakes into the production process and taking corrective actions (Xu, 2011).

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the Analytical Tools in Improving Quality Management

The analytical tools found in increasing quality in BMW play a key role in maintaining the organization and offering it a competitive advantage over its competitors. Quality and superior automobiles have made the company’s brand a worldwide servicing many consumers into the vehicle industry. Improvement plans in quality management are possible through customers’ feedbacks. It gives valuable information to the organization to tailor its services and products considering customers’ expectations.trust my paper Therefore, such feedback has to be critically analyzed so that you can assess the efficiency of this tools as an element of continuous improvement. All feedbacks are extremely advantageous in quality management.

The analysis of sales across all markets which are served by BMW is important in determining the production rates and expansion capabilities. Without such measures it will be difficult for the company to meet up with sales objectives of different regions as a result of underproduction.

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The use of both statistical and non-statistical measures should supply a way to assess the company’s profitability. The revenue forecasts must be met and any deviations analyzed for maximum outputs (Tennant, 2001). BMW key strategies in ensuing continuous improvement should be directed by way of a strong application of this quality control measures, both quantitative and qualitative. The main advantage of such application would have been a conducting of a multi-dimensional approach in managing quality of automobiles being produced through analyzing information in possession of all the stakeholders for maximum output and productivity.

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Ebola virus is just a very dangerous disease which has some strongly pronounced characteristic like severe course, high mortality therefore the development of hemorrhagic syndrome. This virus causes an acute heavy disease which may be life-threatening without proper treatment. For the first time the Ebola virus has been detected in 1976 when there was two outbreaks in the same time: in Nzara, Sudan plus in Yambuku, Democratic Republic of Congo. The second outbreak had been taken place into the village near to the river Ebola from which the illness got its name. Even though the previous outbreaks with this disease have affected a tiny part of the population, in 2014 the Ebola epidemic outbreak spread and affected significantly more than 1,700 people about 900 of whom died. There are two factors of Ebola that are to be taken into account: it results in heavy mortality and is still uninvestigated (Peterson, 2014). The second simple truth is quite frightening, because most people have no idea what direction to go if being infected.

Ebola virus falls in to the Filoviridae category of viruses which also includes Lloviu and Marburg. Into the world you can find 5 forms of these viruses: Zaire, Bundibugyo, Sudan, Reston, and Tai Forest. The first three of those belong to Ebola virus and tend to be connected with large outbreaks in Africa (Draper, 2002). The virus that caused the outbreak in West Africa in 2014 belongs to the species of Zaire.

The viruses that quickly and naturally kill its prey fill people who have fear, though they are not considered the absolute most insidious. The death in just a few days is terrible, but it is inefficient way to spread the illness for the viruses. Hence, historically the high speed viruses like Ebola would quickly burn on their own and acquire back to the principal source, while such slowly emerging viruses as HIV/AIDS spread all over the world.

The scientists believe that the explanation for Ebola virus reappearance lies in the maintenance of the bats’ population in central and western Africa. The asymptomatic good fresh fruit bats transmit the illness to such animals as tiny antelopes and primates. This sort of virus have not spread into the places where these animals are absent. Ebola have broken in to the adult population as a result of their close experience of blood, secretions, organs or other human anatomy fluids of infected animals. However, brisk trade of bushmeat including bats, monkeys, and rats does occur in many elements of Africa, also in Sub-Saharan Africa. Hence, single infected animal could start the complete Ebola virus epidemic in 2014. Besides, the funerary ceremonies where the mourners have the direct experience of the human body of this deceased person can play a substantial role into the transmission of this Ebola virus.

Incubation period of the virus (time interval from virus disease to onset of symptoms) ranges from 2 to 21 days. People become contagious aided by the appearance of this symptoms. 1st symptoms will be the sudden appearance of fever, muscle tissue aches, headache, and sore throat. They have been followed by vomiting, diarrhea, rash, renal and liver failure, and, in certain situations, hemorrhage both internal and external (as an example discharge of blood from the gums, blood in stool).The laboratory findings show the lower quantities of white blood cells and platelets in addition to elevated liver enzymes (Quammen, 2014).

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folks are contagious as long as their blood and excretion like the semen and breast milk contain viruses. People recovered from infection can continue to send the virus up to 7 days after recovery through the semen.

So that you can concur that the observable symptoms are caused especially by Ebola virus the following research is to be made (Klenk, & Feldmann 2004):

– The enzyme-linked immunosorbent assay (ELISA) by taking of antibodies;

– Tests for antigens’ detection;

– Serum neutralization reaction;

– Polymerase chain reaction with reverse transcription (RT-PCR);

– Electronic microscopy;

– Virus isolation in mobile cultures.

The samples gathered from the patients present a exceptionally high biohazard. The laboratory assessment of this samples must be conducted under maximum biological containment.

Discussing the treatment of Ebola virus it is necessary to mention so it will not exist yet. So that you can increase people’s survival it is necessary to hold out the maintenance therapy with intravenous administration of fluids also to treat the particular symptoms. However, currently a number of prospective method of treatment including blood services and products, immune and drug therapies are under evaluation. Because there is no licensed treatment which will be confirmed by the scientists as a method of the virus neutralization, a number of therapies, as an example, blood, immune, and drug therapies are developed.

America in addition has conducted quantity of studies for making a vaccine against the virus. Several kinds of treatment procedures were made on such basis as already infected people. This technique relies upon the concept that antibodies against Ebola virus (proteins developed by defense system of a person in response to the dangerous intruders) may assist the human body in fighting disease. Therefore on this basis special serum has been developed.

The serum is just a section of blood which contains antibodies. Into the past through the outbreaks of Ebola virus it absolutely was extracted from people who have experienced Ebola virus but are not contagious. However their blood still contains advanced level of antibodies against the virus.

The scientists require the requirement of this Ebola virus prevention. Raising awareness in regards to the risk factors of this Ebola virus disease as well as personal protection measures will be the effective ways of reducing the transmission of this disease among the people.

So that you can reduce the risks of this Ebola virus people must be dedicated to the following factors (Alton, 2014):

  • Reducing the risk of disease transmission from wild animals to humans through the associates with infected good fresh fruit bats and monkeys/apes, usage of its raw meat. It is necessary to wear gloves as well as other appropriate protective clothing during the task with animals. Before eating the foodstuff (blood and meat) it is necessary to cook it thoroughly.
  • Reducing the risk of disease transmission from one individual to another as a result of direct or close experience of people who have the Ebola virus symptoms, specially with liquids of these organism. Additionally it is essential to wear gloves and appropriate personal protection garments for the individuals looking after the patients in household conditions. After visiting patients in hospitals or nursing the patients in household conditions is important to scrub the arms regularly.

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Containment measures of this outbreaks include (Jones, 2014):

– fast and safe burial of deceased;

– identification of the individuals who may have the experience of anyone from the Ebola virus infected;

– track of the health status of the people who have had the contacts with patients during 21 days;

– significance of the separation of healthy and unwell people so that you can prevent further transmission;

– significance of appropriate hygiene and maintenance of cleanliness;

– health care providers should always follow standard precautionary measures looking after the unwell regardless of the presumptive diagnosis. The measures will be the following: the basic hand hygiene, respiratory hygiene, using of personal protective equipment, the implementation of safe injection and safe burial of this deceased.

Medical workers must protect their faces (using the front panel or medical mask and glasses) and wear clean non-sterile gown with long sleeves and gloves ( for a few procedures – sterile) through the close contact (closer than one meter) aided by the unwell person infected by Ebola virus. Laboratory workers are also at an increased risk. The samples extracted from people and animals for the diagnostics associated with the Ebola disease must be handled by well-trained staff in suitably equipped laboratories.

World Organization of Health aims to avoid the outbreak of this Ebola virus providing surveillance of the disease brought on by Ebola virus and providing support by developing plans to the countries which are beneath the risk (Wilson, 2014).

In the eventuality of the Ebola virus outbreak, the entire world Organization of Health reacts by supporting the implementation of the surveillance, involvement of regional communities, management of patients, laboratory services, contact tracing, disease control, logistics support, training and support into the application of this burial safe methods.

Ongoing outbreak in West Africa (1st situations were recorded in March 2014) could be the largest and most complicated Ebola outbreak since the detection of this virus in 1976. With this outbreak significantly more people become infected and died when compared with the rest of this outbreaks taken together.

In line with the worst scenarios of virus development, by the conclusion of January 2015 how many people infected by Ebola virus could increase at 100 times up to 550 thousand people. In the event any steps are not undertaken to limit the scope of this current outbreak of this life-threatening virus, how many infected people can make thousands  within just 6 months.

Generally speaking, in line with the opinion of World Organization of Health the Ebola virus continues to spread rapidly into the territory of Western Africa and it’s also very important for all to see or watch the safety precautions to prevent this terrible disease.

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History of Toxins

Toxin lesions are not contagious. They are not transmitted to many other humans or animals. Toxins are formed a long time before they will have penetrated the human body. The tactical employment of toxins is possible in line with the same principles therefore the same practices that are characteristic of chemical weapons. Finally, toxins might be produced not merely by microorganisms but in addition by animals and plants. They even may be prepared synthetically. There are numerous studies of this synthesis of fragments of modern toxins from 10-15 amino acids into the polypeptide chain into the laboratory scale. This fact offers reason to trust that toxins are one of many modern trends in the development of chemical weapons. French scientist Louis Pasteur started the study of toxins. He could be regarded as being the founder of modern immunology. His works were specialized in the establishment of this factors behind rabies. Louis Pasteur postulated the existence of a certain rabies toxin and proposed the strategy of remedy for this disease with the use of anti-rabies serum successfully tested on humans in 1885 (Aktories & Just, 2000). In 1890, German bacteriologist Emil von Behring found that the serum of animals confronted with a tiny (sub-lethal) dose of toxins had preventive curative properties (Aktories & Just, 2000). The consequence of this research had been the development of anti-diphtheria serum. This discovery marked the beginning of immunotherapy of common infectious diseases (Aktories & Just, 2000). However, toxins are really dangerous for humans in large doses.

General Notion on Botulinum Toxin

Roland Langford (2004) affirms that “Botulinum toxin could be the toxic ingredient produced by the bacterium Clostridium botulinum” (p. 158). In 2011, the entire world used about 1 gram of pure toxin in medical and cosmetic purposes. More over, it is estimated that around two kilograms are enough to kill the entire population of this Earth. From soils, spores of clostridium botulinum can enter the foodstuff where they germinate into the shortage of oxygen. As a result, the toxin is accumulated in food. In that method, it can cause poisoning. There could be reproduction of bacteria in the human body during disease of wounds plus in the intestines of infants with out a formed symbiotic microbial community. In every these situations, there is botulinum toxin poisoning. Hence, a pathological condition called botulism develops (Prasad, 2009). You can find 7 different botulinum toxin types – A, B, C1, D, E, F, and G. They differ by structural features and system of action. All types of toxins aside from F and G have an impact on an individual (Krenzelok, 2003).

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The botulinum toxin enters the human body with food or water and gets to the blood through the epithelial cells of the tiny intestine – enterocytes. The toxin can additionally be absorbed into the bloodstream through inhalation of its aerosol. From the blood, it gets to motor neurons. As soon as into the mobile, the poison just isn’t designed for the action of this disease fighting capability. In such a way, the application of certain antibodies towards the toxin for the therapy is beneficial only into the earliest stages of this disease. Botulinum toxin blocks the impulse transmission from the nerve endings towards the muscle tissue. It influences an activity of this release of nerve endings of a neurotransmitter acetylcholine from vesicles. Vesicular transport is important for the life of all of the human cells. There exists a system for the targeted delivery of this vesicles with their destination into the mobile – to the surface of cells or organelles of this vacuolar system – the device of internal membranes, which include the Golgi apparatus, endoplasmic reticulum, and lysosomes. The directed transportation is possible due to the system of mutual recognition of vesicles and destination at the expense of protein binding embedded within their membranes (Ladant, Alouf, & Popoff, 2005). The system of this directed transportation of intracellular vesicles plays a major role in the functioning of nerve cells as their numerous outgrowths form associates with other cells and tend to be functionally distinct. In particular, this system is required for neurotransmitter release and transmission of nerve impulses from neuron towards the muscle tissue. The neurotransmitter is transported towards the nerve ending, which can be saved nearby the presynaptic membrane and is released nearby the neuron excitation the merger with transport vesicles and presynaptic membrane of this neuron. Botulinum toxin violates the conventional process of release of the neurotransmitter acetylcholine by motor neurons splitting one of the molecules essential to bind the vesicles aided by the presynaptic membrane. As a result, the neuromuscular transmission is blocked (Ladant, Alouf, & Popoff, 2005). For that reason, muscle tissue paralysis develops. If they affect respiratory muscles, it may result in death. It is possible to help these patients by mechanical ventilation of lungs. It frequently requires from four to six days. The action of this toxin lasts from weeks to almost a year. After this, transmission of impulses becomes normal. There are two stages of this restoration of neurons after botulinum toxin poisoning. Through the first stage, there is the growth of new nerve endings offering the conventional innervation of muscles. Then, the original function of the nerve ending restores (Ladant, Alouf, & Popoff, 2005).

From 1957 to 2011, the mainly pentavalent vaccine had been used. However, it absolutely was active against toxins of A, B, C, D, and E types. Later, it absolutely was replaced by way of a new vaccine (Krenzelok, 2003). Immunization can be held among the staff working with botulinum toxin in medicine, industry, or research laboratories.

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Botulinum Toxin as a Military gun

Due to the high activity of this toxin, army agencies of different countries considered the likelihood of its use as being a biological gun, along with the terrorist threat. Into the 20th century, new types of the production of botulinum toxin for army and subversive purposes developed into the preparation for chemical and bacteriological warfare. In the United States, during World War II botulinum toxin had been viewed as a promising biological gun. The army centers in the United States, Britain, and Canada considered making use of botulinum toxin of type a for these purposes (Croddy & Wirtz, 2005). This sort is generally accepted as the absolute most dangerous to humans. There exists a version that fighters of this Czechoslovak resistance applied botulinum toxin into the murder of Reinhard Heydrich (Croddy & Wirtz, 2005). In 1971, the UN General Assembly approved the Convention regarding the Prohibition of this Development, Production, and Stockpiling of Toxin Weapons and on Their Destruction. Author Dongyou Liu (2014) states that “Currently, 170 states parties are involved” (p. 1). In 1975, as a result of many years of researches, botulinum toxin of type A was adopted by the usa Army beneath the code XR (Croddy & Wirtz, 2005). Its reserves are saved in Arkansas. The life-threatening outcome for a person may possibly occur within three days. In the air, the spray is beneficial as being a bioweapon within 12 hours (Croddy & Wirtz, 2005). You are able to degas XR only with aqueous solutions of this active chlorine. XR formaldehyde solutions are specially easily deactivated. The biological gun in the form of an aerosol is the most dangerous for the people (Croddy & Wirtz, 2005). It is from the undeniable fact that the toxin is readily absorbed by the mucous membranes of this eyes and upper respiratory tract. Nonetheless, respirators make sure reliable protection against aerosol XR. to guard against the possible poisoning of soldiers during World War II, the usa Department of Defense developed 1st vaccine against botulism (Croddy & Wirtz, 2005).

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Conclusion

These days, botulinum toxin is known as to be one of the more dangerous substances. Entering the human anatomy, the substance causes severe injury to the nervous system, progressive paralysis, and respiratory arrest. Botulinum toxin had been used as being a biological gun on the fronts of World War II. Several decades later, the UN General Assembly approved the Convention regarding the Prohibition of this Development, Production, and Stockpiling of toxic weapons, including botulinum toxin. In my opinion, this convention has saved many everyday lives as without it toxic weapons could possibly be still used.

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Corporate Structure

Corporate structure includes all departments of this organization. Consequently, Al Mafraq comprises of 36 departments that are united by way of a common mission and goals (Launching Mafraq Hospital, n.d.). It has a standard corporate structure that presupposes the existence of the following departments: oncology, laparoscopic surgery, lithotripsy into the endocrine system, vascular surgery, renal & organs transplantation, medical research center, open heart surgery, urology, cardiac cath, pediatric surgery, thoracic surgery, ENT, cochlea implant surgery, plastic cosmetic surgery, neurology, acupuncture therapy, neurosurgery, endocrinology, dermatology, ophthalmology, gynecology, nephrology, physiotherapy, neonatology, emergency rooms, rheumatology, and obstetrics (Launching Mafraq Hospital, n.d.). As a result, corporate structure of Al Mafraq Hospital consists into the division of this organization in accordance with its functions and medical services. Moreover, you need to mention that each and every department is supervised by the most effective managers that bear obligation for the proper functioning of all of the departments in Al Mafraq Hospital.

Corporate Social Responsibility

Corporate social responsibility (CSR) could be the company’s initiatives offering its social and environmental well-being. Corporate social obligation is on the basis of the organization’s actions for making a positive image and gaining a reputation that will benefit town (Bhattacharya & Sen, 2004). One should mention that CSR takes under consideration consumer perspective. Because of this reason, CSR has changed into a main-stream with regards to creating shared values not merely for business but in addition the society. It indicates that the organization should not take care of its competitive advantage but alternatively its moral and ethical reputation within industry. Corporate social obligation is on the basis of the following categories: environment, philanthropy, and ethical labor techniques (Crowther & Aras, 2008). Corporate social obligation is conditional and ambivalent once the company implements this policy out from the prerequisite if you are socially responsible and having economic perspectives with regards to the corporation. The principles of CSR are transparency, accountability, and sustainability (Aras & Crowther, 2008).

Industry explanation

Al Mafraq Hospital is just a medical product that employs around 2,000 professional medical workers. It indicates it is given the hr that are prepared to any innovations and changes. The corporation supports trauma program and operates once the largest burn product in the UAE. The mission of Al Mafraq Hospital is always to improve medical industry rendering it more innovative and progressive. The corporation has all perspectives money for hard times growth since it gets the assets equaling to $750 million, which allows it to create a fresh campus by 2017 (Introducing Mafraq Hospital, n.d.). More over, Al Mafraq Hospital undergoes emiratization that presupposes the employment associated with the UAE physicians. The skills of Al Mafraq Hospital are evident due to its honors such as for example Sheikh Khalifa Excellence Awards and the 2011 Overseas Business Award. A medical facility is accredited to produce services. More over it absolutely was re-accredited in 2014.

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Al Mafraq Hospital’s CSR Policy and Its Implementation

Al Mafraq Hospital applies a basic way of CSR policy. Consequently, its corporate philosophy relies on the following concepts: accountability, transparency, integrity, and trust (Crowther & Ortiz Martinez, 2004). However, this basic approach enables ethical decision creating and commitment to the noble mission and vision of this organization. Al Mafraq’s aspirations are regarding meeting needs of these customers and becoming the most qualitative medical centre. Their commitment means business services and customer support services. Al Mafraq Hospital’s stakeholders are consumers, partners, employees, and society. They have been united by way of a common objective of providing medical services. Al Mafraq Hospital seeks to play a role in the sustainable development of the society by creating new values, being ethical and moral while working with consumers, and providing qualitative medical services. Its major policy is founded on the social obligation.

The implementation of CSR policy at Al Mafraq Hospital has been performed considering that the foundation of this organization. By founding Al Mafraq Hospital, its executive staff was able to develop its vision and mission straight away to appreciate their objectives aided by the help of managers and employees. At present, Al Mafraq Hospital normally striving to boost CSR awareness. More over, this organization supports the regulations regarding anti-corruption, environment, labor, and human liberties. First, Al Mafraq Hospital has sound corporate activities adapted towards the domestic and international legislation. More over, the corporation maintains constructive relationships with the us government as well as other businesses.